Richard J Jurevic, DDS, PhD Assistant Professor of Biological Sciences School of Dental Medicine Case Western Reserve University

Answers questions in the following forums:

• Dental and Oral Health (Adults)
• Gum Diseases
• HIV and AIDS
• Mouth Diseases
• Research Center

NetWellness Articles associated with this Author:

	Article Name	Forum
	What Causes White Patches in the Mouth and Tongue?	Mouth Diseases

Grants:

• Epithelial immunity and oral comlications of HIV/AIDS The genetic variation of innate immune genes with oral manifestations of HIV/AIDS
  NIH/NIDCR R56 grant to investigate the realtionship of genetic variations in the defensin gene cluster and Toll-like receptors with the susceptibility and development of oral disease associated with HIV/AIDs (HPV, OHL, CA)
• Defensin gene cluster variation and Candida carriage
  The K23 mentored, patient oriented,clinical research grant involves the investigation and development of high-throughput genetic assays to study the complex genetic variations in the Defensin gene cluster with susceptibility to oral yesst infection in immunocompromised and non-immune compromised individuals. The defensins are epthelial expressed antimicrobial peptides involved with innate immume protection of mucosal surfaces. We are investigating the association of SNPs and CNVs with peptide expression and susceptibility to oral yeast infection in high risk patieints.
• Oral Mucosal immunity in Vulnerable HIV infected Populations “The genetic variation of innate immune genes with oral manifestations of HIV”
  NIH/NIDCR Program Project 1P01DE019759-01, The major goals for this program project is to identify variations within innate and adaptive immune defense mechanisms that may impact susceptibility and or progression of oral mucosal pathology associated with HIV/AIDS. Project 4 will focus on identifying possible genetic variations within the genes that impact innate and adaptive immunity.