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Friday, April 18, 2014
The following chart shows the results of the 2005 Sleep America Poll that relate to symptoms of insomnia. More than half of those polled reported experiencing symptoms of insomnia (indicated by the Dragging Duos, Overworked, Overweight, and Overcaffeinated, and the Sleepless and Missin' the Kissin' groups).
Source: 2005 Sleep America Poll, National Sleep Foundation
Insomnia can involve difficulty in falling asleep, waking up frequently at night, waking up too early in the morning, or waking up and not feeling refreshed. Insomnia is not a disease but a symptom. It can be caused by an underlying sleep disorder, or might be brought on by something as simple as a change in schedule, a stressful event at work, or an afternoon cup of coffee. Insomnia becomes more common as people grow older, and is also more common in women.
Sleep plays an important role in our overall well-being. Many body functions suffer if we don't have regular sleep:
In falling asleep and sleeping, people go through predictable stages -
With normal aging, people spend more time in light sleep, less time in deep sleep and have less REM sleep.
With age, sleep becomes less "efficient." People take longer to fall asleep, wake up more frequently and spend more time awake. Older people also:
Are you dissatisfied with your sleep? Do you routinely become sleepy during the day? Does your bed partner notice any unusual behavior while you sleep? Answering "yes" to any of these questions may mean that you have a sleep disorder. Before considering non-prescription or prescription sleep medications, try the following:
Certain medications can interfere with normal sleep patterns. Following is a list of drugs that can cause insomnia:
|Drug||Common Source or Use|
|Alcohol||Found in beer, wine, liquor|
|Anticonvulsants||Used to treat epilepsy|
|Bronchodilators||Used to treat asthma, emphysema|
|Caffeine||Found in coffee, tea, soft drinks, over-the-counter pain medications|
|Cocaine||Used as a stimulant (illegal)|
|Estrogen||Used in hormone replacement therapy|
|Levodopa||Used to treat Parkinson's Disease|
|MAO inhibitors||Used to treat depression and mental health problems|
|Ritalin||Used to control hyperactivity and ADD|
|SSRIs (such as prozac)||Used to treat depression and mental health problems|
|Steroids||Used to treat emphysema, asthma and many other chronic diseases|
|Sympathomimetics||Found in cold remedies|
|Theophylline||Used to treat asthma|
|Thyroid hormone||Used to treat underactive thyroid (metabolic disorders)|
|Date||Bedtime||Time to fall asleep||Sleep quality
>(1 to 5)
|Total sleep time||Level of Refreshment
>(1 to 5)
>(1 to 5)
|3/26||11pm||1 hour||3||5 hours||3||4||1 cup coffee 3pm|
|3/27||12am||Over an hour||3||6 hours||3||3||Fight with boss|
|3/28||11pm||25 min?||4||7 hours||4||3||No caffeine|
|3/29||12am||45 min||3||5 hours||3||3||22 oz coke 3pm|
Depression can take a toll on your ability to sleep. The self-administered Patient Health Questionnaire 9 is a test for diagnosing depression that you can take yourself. If you are concerned about depression, ask you health care provider about taking this test.
Good sleep hygiene describes methods you can use to encourage drifting off into quality sleep. Some examples follow:
Non-prescription medications for insomnia are usually antihistamines and may have significant side effects including:
Additional concerns with both non-prescription and prescription sleep medications are that they can be habit-forming and addictive. More recently, natural remedies have been promoted to help people sleep. Examples include valerian and melatonin:
There are downsides to over-the-counter melatonin and valerian, too. Because melatonin is an animal product, it can be contaminated with viruses or other problems. In addition, the FDA does not regulate valerian and over-the-counter melatonin, so the purity and potency may vary widely. Many researchers are skeptical of the effectiveness of either valerian or over-the-counter melatonin in relieving insomnia.
While there are varying opinions on the over-the-counter sleeping aids mentioned above, all experts agree: You should never use alcohol, illicit drugs or medications prescribed for a friend for your sleep problems.
There are three commonly recognized classes of sleep medications. The oldest of these classes is the benzodiazepines (e.g. triazolam, flurazepam). These medications are effective for short-term treatment of insomnia, but should always be used under a physician's supervision. Side effects typically include sedation the next day, impairment of performance, and particularly in elders, dizziness and falls. Newer, non-benzodiazepine medications, such as zolpidem, zaleplon, and eszopiclone, work similar to the benzodiazepines but may avoid some of the benzodiazepine side effects. Because these medications have different duration of action, some are more suited for treating sleep disturbance in the middle of the night. The newest prescription class of medication is the melatonin agents such as ramelteon. Ramelteon is not a controlled substance. Other medications, such as sedatives and antidepressants (e.g. trazodone) are also used as sleep aids.
The benefits, side effects and contraindications (non-compatible drugs) vary for each class of sleep medication. Your healthcare provider can help you select the best sleep medication for your needs.
Kryger, Meir H., Thomas Roth, and William C. Dement (eds). Principles and practice of sleep medicine, 4th ed. Philadelphia, PA: Elsevier/Saunders, 2005.
Last Reviewed: Jul 28, 2006
Jeffrey L Susman, MD
Associate Professor and Chief of Surgical Oncology
College of Medicine
University of Cincinnati