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Prostate Cancer

Allergies and Inflammation Effect on PSA Scores



I have been taking Benadryl for severe allergic reaction (12 or more tablets per day, and using the skin scream for 3 days. My PSA is 16, 4 times what it had been in March. Had hives and several other asthma/allergy reactions going on prior to test. Is this related and/or could have an effect on the outcome? Did not fast before the test.


It certainly is possible that severe inflammation could cause your PSA to be elevated if you had inflammation of the prostate as well. It would certainly be worth repeating once your severe allergy has resolved.

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Response by:

Lee E Ponsky, MD Lee E Ponsky, MD
Associate Professor of Urology
School of Medicine
Case Western Reserve University