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Pharmacy and Medications

Mixing Medications



I am currently taking 1 Olanzapine 10mg tablet before bed. I have a cold now and was wondering if it was safe to mix Alka-Seltzer Plus night formula with it? I try to be very careful when mixing medications.


There are multiple ingredients in the Alka-Seltzer PlusĀ® Night Cold Formula. None of these ingredients interacts significantly with olanzapine; however, you may experience some additional drowsiness.

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Response by:

Michael  Ganio, PharmD Michael Ganio, PharmD
Clinical Applications Pharmacist
Wexner Medical Center
The Ohio State University